01 - Preheat oven to 350°F. Grease and line a 9x5-inch loaf pan with parchment paper.
02 - Whisk together flour, baking powder, baking soda, and salt in a medium bowl; set aside.
03 - Using an electric mixer or whisk, cream softened butter and sugar until light and fluffy, about 2 to 3 minutes.
04 - Beat in eggs one at a time, mixing thoroughly after each addition.
05 - Mix in Greek yogurt or sour cream, milk, orange zest, orange juice, and vanilla extract until uniform.
06 - Gradually fold dry ingredients into wet mixture until just combined; avoid overmixing.
07 - Toss cranberries with 1 tablespoon of flour to prevent sinking, then gently fold into batter.
08 - Pour batter into prepared pan, smooth the surface, and bake for 50 to 55 minutes until a toothpick inserted in the center comes out clean.
09 - Allow loaf to cool in pan for 10 minutes, then transfer to a wire rack to cool completely.
10 - Whisk powdered sugar with fresh orange juice and drizzle over cooled loaf if desired.